Scientists led by a group of researchers at The Scripps Research Institute (TSRI) in La Jolla, CA, have discovered some of the key proteins involved in one type of DNA repair gone awry.
May 22, 2014
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An international research consortium led by the Universitat Autònoma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending ...
Apr 25, 2013
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Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece ...
Mar 21, 2024
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A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging.
Dec 19, 2023
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DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory ...
Jan 28, 2016
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Smoking while pregnant causes severe DNA damage to cells in the placenta and significantly impairs its function, new University of Otago research suggests.
Dec 4, 2013
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Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy. Two of the biomarkers involved are the ...
Jul 26, 2017
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Mutations driving cancer development leave behind specific 'scars," so-called mutational signatures, in the genome. In principle, they allow for profiling of the cancer type and its development—but the noisy environment ...
May 9, 2018
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DNA is the computer code that programs every event in the body. Despite the importance of DNA fidelity, as the body develops, cells grow and replicate, DNA is constantly turned over. This repeated process can compromise the ...
Aug 31, 2017
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After finishing his PhD in molecular genetics in the late 1990s, Daniel Anderson found himself conflicted about what to do next: He enjoyed science, but wanted to find a way to have a direct impact on human health.
Feb 17, 2015
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