Oncology & Cancer

Drug-resistant cancer cells create own Achilles heel

The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...

Oncology & Cancer

New cancer strategies promising, says researcher

Dr. Tim Fenton, an expert in cancer research at the University, says the announcement of new strategies to overcome the evolution of drug resistance in tumours could dramatically increase the effectiveness of cancer therapies.

Genetics

Poverty leaves a mark on our genes

A new Northwestern University study challenges prevailing understandings of genes as immutable features of biology that are fixed at conception.

Genetics

A quick path to antimalarial resistance

Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new ...

Oncology & Cancer

How prostate cancer becomes treatment resistant

The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...

Medications

Cocktail of common antibiotics can fight resistant E. coli

Today, many disease-causing bacteria acquire resistance genes, which make antibiotic treatment ineffective. One gene especially—CTX-M-15, encoding an extended spectrum beta-lactamase (ESBL)—can lead to resistance in E. ...

Oncology & Cancer

Fighting cancer one cell at a time

A team of scientists from Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by targeting the evolution of cancer cells. This approach ...

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