Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive. To identify previously unknown genes ...
Apr 4, 2023
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Growing resistance to antibiotics and other antimicrobial treatments is a serious global healthcare challenge. A new study in Antibiotics demonstrates a method for tracking the spread of genes for antimicrobial resistance ...
Mar 28, 2023
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An international team led by researchers from MacCallum Cancer Center in Melbourne, Australia, examined 391 tumor tissues from about 270 multisite autopsy samples collected from 15 individuals with end-stage high-grade serous ...
In a study published in Human Genetics, QUT Professor Dale Nyholt and QUT Ph.D. researcher Rafiqul Islam, describe using large-scale genome-wide associations studies (GWAS) summary statistics to analyze hundreds of thousands ...
Feb 23, 2023
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Researchers at The University of Texas at Dallas have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found ...
Dec 12, 2022
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Worldwide, more pathogens are becoming resistant to today's antibiotics. As antibiotics lose their efficacy, infections that were once easy to treat can give rise to fatal illnesses.
Nov 15, 2022
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Scientists have shown how stomach cancers can dodge the effects of a promising new experimental treatment—raising the possibility of outsmarting cancer by predicting drug resistance in advance.
Oct 25, 2022
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Alveolar rhabdomyosarcoma is a type of rare pediatric tumor. For more than 40 years there have not been any new developments regarding treatment. Research led by Prof. Dr. Anton Henssen at Charité University Berlin has now ...
Sep 19, 2022
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The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding from the Cleveland Clinic's Lerner Research Institute.
Sep 12, 2022
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A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. ...
Aug 10, 2022
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