Medical research

Drug cocktail reduces aging-associated disc degeneration

Chronic back pain affects upwards of 15 million adults in the US, racking up billions in healthcare costs and lost work days. Degeneration of the discs that cushion and support vertebrae, a common occurrence of aging, is ...

Oncology & Cancer

A novel function of noncoding RNA in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today in the leading international scientific journal Proceedings of the National Academy of Sciences, reveals ...

Neuroscience

'Zombie cells' hold clues to spinal cord injury repair

Mammals have a poor ability to recover after a spinal cord injury, which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment ...

Medical research

Researchers identify target for senolytic drugs

In a study recently published in Nature, University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

Medical research

Scientists find mechanism that eliminates senescent cells

Scientists at UC San Francisco are learning how immune cells naturally clear the body of defunct—or senescent—cells that contribute to aging and many chronic diseases. Understanding this process may open new ways of treating ...

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