Inhibiting a key enzyme that controls a large network of proteins important in cell division and growth paves the way for a new class of drugs that could stop glioblastoma, a deadly brain cancer, from growing.
Feb 12, 2021
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A potentially effective treatment for diabetic retinopathy, a disease that swells and scars the retina, has been developed by an Université de Montréal scientist and investigator at Maisonneuve-Rosemont Hospital Research ...
Feb 11, 2021
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Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...
Jan 08, 2021
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254
Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science ...
Dec 15, 2020
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How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a "zombie" cell state called senescence, Medical College of Georgia ...
Dec 07, 2020
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In human, the skin is one of the organs that exhibit early-onset aging-associated dysfunction. As a critical physical barrier, the skin is composed of a variety of cell types including fibroblasts and keratinocytes. Due to ...
Nov 27, 2020
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I recently visited an 83-year-old patient in the hospital after EMTs rushed her to the ER with an infected leg wound. Her ordeal started inconspicuously when she bumped into the sharp edge of a table and developed a small ...
Nov 24, 2020
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NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...
Nov 16, 2020
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443
A preclinical study conducted at the Institute of Oncology Research (IOR, affiliated to USI Università dellaSvizzera italiana) reveals the role of aging cells in the formation of metastases and identifies a drug capable ...
Nov 13, 2020
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Despite the great advances in cancer research in recent years, treatments that can cause very severe adverse effects are still used. This is the case of neuropathy caused by chemotherapy with platinum derivatives, such as ...
Sep 29, 2020
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