Medications

How new ketamine drug helps with depression

On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made ...

Psychology & Psychiatry

When neurons are out of shape, antidepressants may not work

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent ...

Neuroscience

Researchers point to a common cause in sudden death syndromes

Sudden Infant Death Syndrome (SIDS) and Sudden Unexpected Death in Epilepsy (SUDEP) are syndromes that share many medical similarities but whose physiological causes are poorly understood. An opinion article publishing March ...

Psychology & Psychiatry

New study may help guide treatment of pediatric anxiety

Researchers from the University of Cincinnati (UC) examined common medications prescribed for children and adolescents with anxiety disorders, to determine which are the most effective and best-tolerated. This study revealed ...

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Serotonin

"Serotonin" redirects here. For the professional wrestling stable, see Serotonin.

Serotonin (pronounced /ˌsɛrəˈtoʊnən/) is a monoamine neurotransmitter. It is found extensively in the gastrointestinal tract of animals, and about 80 to 90 percent of the human body's total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons in the central nervous system (CNS) where it has various functions, including control of appetite, mood and anger.

Serotonin is found not only in animals, but also in fungi and plants, including fruits and vegetables.

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