Genetics

Researchers explore role of androgens in shaping sex differences

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas. Understanding the regulatory mechanisms associated ...

Oncology & Cancer

Enhanced melanoma vaccine offers improved survival for men

A second-generation melanoma vaccine being developed at UVA Cancer Center improves long-term survival for melanoma patients compared with the first-generation vaccine, new research shows. Interestingly, the benefit of the ...

Sex

In biology, sex is a process of combining and mixing genetic traits, often resulting in the specialization of organisms into male and female types (or sexes). Sexual reproduction involves combining specialized cells (gametes) to form offspring that inherit traits from both parents. Gametes can be identical in form and function (known as isogametes), but in many cases an asymmetry has evolved such that two sex-specific types of gametes (heterogametes) exist: male gametes are small, motile, and optimized to transport their genetic information over a distance, while female gametes are large, non-motile and contain the nutrients necessary for the early development of the young organism.

An organism's sex is defined by the gametes it produces: males produce male gametes (spermatozoa, or sperm) while females produce female gametes (ova, or egg cells); individual organisms which produce both male and female gametes are termed hermaphroditic. Frequently, physical differences are associated with the different sexes of an organism; these sexual dimorphisms can reflect the different reproductive pressures the sexes experience.

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