Genetics

Addressing a complex world of pain in a single gene difference

A single letter difference in a single gene, inherited from both parents, spells a lifetime of anemia and pain for 20 million people, mostly of African ancestry, worldwide. Sickle cell disease (SCD) causes red blood cells ...

Diseases, Conditions, Syndromes

Transplant beneficial for kidney failure in sickle cell

(HealthDay)—Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality, according to a study published online Feb. 25 in the Clinical Journal of the American ...

Medications

Sickle cell target could treat COVID

Scientists have found a way to lower stroke risk in sickle cell patients that opens a gateway of potential treatments for inflammation and clotting stemming from conditions such as COVID-19. For the first time, they investigated ...

Diseases, Conditions, Syndromes

CRISPR technology to cure sickle cell disease

University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients' blood ...

Genetics

New taxonomy of non-skeletal rare disorders with impact on bone

Thanks to major progress in the understanding and management of rare congenital diseases and syndromes, many patients with these rare disorders are now living longer lives. With this progress it has become apparent that many ...

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