Alzheimer's disease & dementia

'Exhausted' immune cells may drive Alzheimer's

Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...


Uncovering the role of somatostatin signaling in the brain

Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and risk-taking-like behavior ...


How heavy alcohol consumption increases brain inflammation

For people with alcohol use disorder (AUD), there is a constant, vicious cycle between changes to the brain and changes to behavior. AUD can alter signaling pathways in the brain; in turn, those changes can exacerbate drinking.

page 1 from 9