Oncology & Cancer

Lymphoma mutation yields super-competitive immune cells

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional ...

Medications

Study sheds new light on a promising antidepressant

Ketamine, a well-known anesthetic used in smaller doses as a party drug, was hailed as a "new hope for depression" in a Time magazine cover story in 2017. Two years later, the arrival of the first ketamine-based antidepressant—the ...

Medical research

Amoeba biology reveals potential treatment target for lung disease

In a series of experiments that began with amoebas—single-celled organisms that extend podlike appendages to move around—Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated ...

Diseases, Conditions, Syndromes

TB study reveals potential targets to treat and control infection

Researchers at the Southwest National Primate Research Center (SNPRC) at Texas Biomedical Research Institute (Texas Biomed) may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium ...

Genetics

Still too soon to try altering human embryo DNA, panel says

It's still too soon to try to make genetically edited babies because the science isn't advanced enough to ensure safety, says an international panel of experts who also mapped a pathway for any countries that want to consider ...

Oncology & Cancer

Revealed: How cancer develops resistance to treatment

Cancer cells can turn on error-prone DNA copy pathways to adapt to cancer treatment, a breakthrough study published in the journal Science has revealed. Bacteria use the same process, termed stress-induced mutagenesis, to ...

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