Diabetes

DPP-4 inhibitor has dissociated effects on β-cell function

(HealthDay)—For healthy adults and individuals with well-controlled type 2 diabetes (T2D), a single dose of the dipeptidyl peptidase-4 inhibitor sitagliptin is associated with increased standardized insulin secretion, with ...

Diabetes

Sitagliptin stimulates distal tubular natriuresis in T2DM

(HealthDay)—For patients with type 2 diabetes, the dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin stimulates distal tubular natriuresis, according to a study published online May 26 in Diabetes Care.

Diabetes

Metformin, sitagliptin prolong normoglycemia remission in DKA

(HealthDay)—For patients with new-onset diabetic ketoacidosis (DKA) and severe hyperglycemia, metformin and sitagliptin treatment after normoglycemia remission correlate with increased relapse-free survival and prolonged ...

Diseases, Conditions, Syndromes

Which diabetes drug is best for diabetics with kidney disease?

Some blood-sugar-lowering drugs have caused kidney problems in patients with type 2 diabetes, so physicians are especially cautious when prescribing these agents to diabetics who also have chronic kidney disease (CKD).