Professor Megumu K. Saito and his colleagues have revealed that SMN, a protein involved in spinal muscular atrophy (SMA), promotes the functional maturation of mitochondria by regulating miRNA expression along with MYOD1 ...
Feb 17, 2023
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A recent paper published in the Journal of Physiology deepened the case for the youthfulness-promoting effects of exercise on aging organisms, building on previous work done with lab mice nearing the end of their natural ...
Jan 17, 2023
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The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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A group led by Associate Professor Makoto Ikeya has established a new method to generate mesenchymal stem cells (MSCs) from iPS cells via neural crest cells (NCCs) without animal-derived elements. It is expected to be used ...
Sep 28, 2022
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The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana ...
Sep 11, 2022
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Blocking the mutant protein with an antibody didn't stop the strange, abnormal bone growths in mice. But the knowledge gained could steer scientists toward more promising approaches, report researchers from UConn and Alexion ...
Jun 17, 2022
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In the gym, you are not just pumping iron, you are oxygenating muscle cells which keeps those muscles healthy, strong and growing—a process called hypertrophy, or an increase in muscle mass due to an increase in muscle ...
Apr 27, 2022
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Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.
Apr 5, 2022
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Increased levels of blood fats in people with type 2 diabetes and obesity are more harmful than previously thought, a new study has found.
Apr 1, 2022
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Researchers at the Hong Kong University of Science and Technology (HKUST) have discovered the constructive role of a protein in driving the skeletal muscle stem cell activation to repair muscle following damage, laying the ...
Feb 24, 2022
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