Immunology

Systemic lupus erythematosus linked to altered gut microbiome

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain. The gut "microbiome"—all ...

Diseases, Conditions, Syndromes

Belimumab promising in combination therapy for refractory lupus

For patients with systemic lupus erythematosus (SLE) refractory to conventional treatment, belimumab after rituximab significantly reduces serum immunoglobulin (Ig)G anti-double stranded DNA (dsDNA) levels and the risk for ...

Diseases, Conditions, Syndromes

Mortality highest for Asians, Hispanic/Latinos with lupus

(HealthDay)—Standardized mortality ratios (SMRs) of observed-to-expected deaths are increased for patients with systemic lupus erythematosus (SLE) and are especially high for Asians and Hispanic/Latinos, according to research ...

Diseases, Conditions, Syndromes

Some lupus erythematosus cases tied to drug exposure

(HealthDay)—Some cases of subacute cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) are drug-induced, according to a study published online Sept. 2 in JAMA Dermatology.

Diseases, Conditions, Syndromes

New test method can offer safer dosages of hydroxychloroquine

Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with the rheumatic disease systemic lupus erythematosus (SLE). ...

Genetics

Race-specific lupus nephritis biomarkers

University of Houston Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, Chandra Mohan, and his team have discovered a difference in urinary biomarker proteins of lupus nephritis (LN) in patients ...

Arthritis & Rheumatism

Peripheral nervous system events not common in lupus

(HealthDay)—Peripheral nervous system (PNS) disease is a component of systemic lupus erythematosus (SLE) disease activity and has a significant negative impact on health-related quality of life, according to a study published ...

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