Northwestern Medicine scientists have demonstrated that cancer cells – and not normal cells – can be killed by eliminating either the FAS receptor, also known as CD95, or its binding component, CD95 ligand.
Mar 21, 2014
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For the first time, large-scale information on the biochemical makeup of small interfering RNA (siRNA) molecules is available publicly. These molecules are used in research to help scientists better understand how genes function ...
Dec 11, 2013
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(Medical Xpress)—An international team of researchers has discovered a way to silence the genes that cause transthyretin amyloidosis—a fatal genetic disease. In their paper published in the New England Journal of Medicine, ...
Researchers have developed a new drug delivery system that allows inhalation of chemotherapeutic drugs to help treat lung cancer, and in laboratory and animal tests it appears to reduce the systemic damage done to other organs ...
May 22, 2013
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New classes of drugs that can silence specific genes, such as small interfering RNAs (siRNAs), offer great therapeutic potential. But the specific delivery of siRNAs to target cells to exert their effects remains a significant ...
Apr 10, 2013
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New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).
Jan 23, 2013
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Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically increases the ...
Dec 21, 2012
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Jillian Shapiro, a third-year graduate student at the Icahn School of Medicine at Mount Sinai, has been named to the second annual Forbes "30 Under 30" list in "Science and Health." The honorees "reflect the way that the ...
Dec 20, 2012
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(Medical Xpress)—Until recently, medical researchers had little hope of experimentally manipulating naïve T cells to study their crucial roles in immune function, because they were largely impenetrable, says polymer scientist ...
Oct 11, 2012
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Some of the body's own genetic material, known as small interfering RNA (siRNA), can be packaged then unleashed as a precise and persistent technology to guide cell behavior, researchers at Case Western Reserve University ...
Aug 27, 2012
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