Cardiology

An atomic view of the trigger for the heartbeat

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their function, malfunctions, ...

Cardiology

Can obesity limit antiarrhythmic drug effectiveness?

Atrial fibrillation, also known as AFib, is the most common type of irregular heartbeat, and it is associated with increased mortality. While researchers have identified a causal link between obesity and AFib, the underlying ...

Neuroscience

Video: Scientists visualize pain's pathway

The lab of Stephen Waxman, Bridget M. Flaherty Professor of Neurology and of Neuroscience, has identified the key role of sodium channels arrayed on nerve cells in experience of pain.

Medications

Scientist searches for alternatives to opioids

Since ancient times, humans have used opium and its derivatives to block pain. Yet in all that time, no one has found a solution to two main side effects of opioids—addiction and overdose.

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