Northwestern Medicine scientists have mapped the complete structure of a voltage-gated sodium channel, proteins in the membrane of cells that play an important role in many diseases. The findings were published in Nature ...
Apr 4, 2017
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In epilepsy, nerve cells lose their usual rhythm, and ion channels, which have a decisive influence on their excitability, are involved. A team of researchers under the direction of the University of Bonn has now discovered ...
Nov 19, 2015
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For years, a multidisciplinary team of Johns Hopkins researchers has tracked an elusive creature, a complex of proteins thought to be at fault in some cases of sudden cardiac death. As they report Nov. 5 in the online edition ...
Nov 5, 2014
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Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice.
May 22, 2014
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Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. This may come as a surprise to the millions of Americans who receive inhaled ...
Apr 21, 2014
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Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.
Jan 9, 2014
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Dravet syndrome is a rare and severe form of epilepsy caused primarily by inherited loss-of-function mutations in a gene called SCN1A. This gene encodes a sodium ion channel known as Nav1.1 and is required for the proper ...
Sep 20, 2013
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According to new research on epilepsy, zebrafish have certainly earned their stripes. Results of a study in Nature Communications suggest that zebrafish carrying a specific mutation may help researchers discover treatments ...
Sep 3, 2013
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A low dose of the sedative clonazepam alleviated autistic-like behavior in mice with a mutation that causes Dravet syndrome in humans, University of Washington researchers have shown.
Aug 22, 2012
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University of North Carolina scientists have uncovered a new strategy that may one day help people with cystic fibrosis and chronic obstructive pulmonary disorder better clear the thick and sticky mucus that clogs their lungs ...
Jul 13, 2012
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