Around half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in various states of decay like an old fashioned 'pull your own' junkyard where parts ...
The growth of solid tumors is frequently driven by mutations in key proto-oncogenes. For non-small-cell lung cancers (NSCLC), somatic mutations in the KRAS (Kirsten RAt Sarcoma virus) gene turn it into an oncogene that renders ...
(Medical Xpress)—Perhaps the boldest attempt to date at a single unified explanation of cancer is that offered by Albert Szent-Gyorgi in his classic book, The Living State. That was over 40 years ago. His insights on the ...
Genetic mutations are commonly studied because of links to diseases such as cancer; however, little is known about mutations occurring in healthy individuals. In a study published online in Genome Research, researchers detected ...
Apr 23, 2014
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A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which is implicated ...
Sep 4, 2012
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New research from Oregon Health & Science University describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos.
Mar 8, 2024
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Psoriasis—a chronic skin condition—is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.
Oct 26, 2023
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What if Alzheimer's disease left its mark on the embryo? Khadijeh Shabani and her colleagues from the Brain Development team led by Bassem Hassan (Inserm) at Paris Brain Institute show that the amyloid precursor protein (APP) ...
Jun 16, 2023
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The first comprehensive study of somatic mutations in normal human small intestine has been conducted by researchers at the Wellcome Sanger Institute and their collaborators. The findings revealed that an enzyme named APOBEC1 ...
Jan 27, 2023
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Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases. A first-of-its-kind study from Boston Children's Hospital now shows that the cells that ...
Aug 12, 2022
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