Neuroscience

Untangling the where and when of walking in the brain

Imagine walking on two treadmills at the gym, one side moving faster than the other. Would you be able to adapt to this change and come up with a new way of walking, or would you stagger and stumble as your legs falter about, ...

Alzheimer's disease & dementia

Researchers reverse cognitive impairments in mice with dementia

Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the ...

Neuroscience

Mental maps: Route-learning changes brain tissue

Fifteen years ago, a study showed that the brains of London cab drivers had an enlargement in the hippocampus, a brain area associated with navigation. But questions remained: Did the experience of navigating London's complex ...

Health

Adolescents' high-fat diet impairs memory and learning

A high-fat diet in adolescence appears to have long-lasting effects on learning and memory during adulthood, a new study in mice finds. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in ...

Neuroscience

Mapping blank spots in the cheeseboard maze

(Medical Xpress)—During spatial learning, space is represented in the hippocampus through plastic changes in the connections between neurons. Jozsef Csicsvari and his collaborators investigate spatial learning in rats using ...

Neuroscience

Lithium restores cognitive function in Down syndrome mice

Down syndrome is a neurodevelopmental disorder that is the leading cause of genetically defined intellectual disability. In the brain, Down syndrome results in alterations in the connections between neurons and a reduction ...

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