Medical research

Manufacturing spermatogonia stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...

Gerontology & Geriatrics

How age affects male fertility

In 2012, proud dad Ramjit Raghav made global headlines when he became a father at the age of 96. He had beaten the record for the world's oldest dad—a record he'd set himself, two years earlier, at the age of 94.

Diseases, Conditions, Syndromes

COVID-19 infection may reduce fertility in men

COVID-19 may negatively affect sperm quality and reduce fertility in men, according to research published in Reproduction. The study indicates that COVID-19 infection can cause increased sperm cell death, inflammation, and ...

Health

High-fat diet in childhood may affect sperm later in life

New research in mice suggests that a high-fat diet early in life may impair male fertility in adulthood. The first-of-its-kind study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism.

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Spermatozoon

A sperm, from the ancient Greek word σπέρμα (seed) and ζῷον (living being) and more commonly known as a sperm cell, is the haploid cell that is the male gamete. It joins an ovum to form a zygote. A zygote is a single cell, with a complete set of chromosomes, that normally develops into an embryo.

Sperm cells contribute half of the genetic information to the diploid offspring. In mammals, the sex of the offspring is determined by the sperm cell: a spermatozoon bearing a Y chromosome will lead to a male (XY) offspring, while one bearing an X chromosome will lead to a female (XX) offspring (the ovum always provides an X chromosome). Sperm cells were first observed by Anton van Leeuwenhoek in 1677.

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