News tagged with statins

Related topics: heart disease · drug · heart attack · cholesterol

Estimating cost when it comes to novel therapies

When it comes to patient care, finding the best treatment can sometimes include finding an equal, yet more economical solution. Rather than introducing a costly new medication, for some patients changing current dosages or ...

May 17, 2017
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Statins don't cause muscle pain: study

Cholesterol-lowering statin drugs may have been wrongly blamed for muscle pain and weakness, said a study Wednesday that pointed the finger at a psychological phenomenon called the "nocebo" effect.

May 03, 2017
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Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

This text uses material from Wikipedia, licensed under CC BY-SA

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