News tagged with statins

Related topics: heart disease · drug · heart attack · cholesterol

Statins to prevent scar tissue in the eye?

According to a Finnish study, statin medication seems to reduce the risk of repeated surgery in patients who undergo a vitrectomy to treat a detached retina. The researchers believe that statins might prevent the formation ...

3 hours ago
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HDL and kidney injury after surgery

Higher concentrations of high-density lipoproteins—HDL, the "good" cholesterol—may be protective against acute kidney injury (AKI) after cardiac surgery, Vanderbilt researchers have discovered. AKI affects up to 30 percent ...

6 hours ago
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Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

This text uses material from Wikipedia, licensed under CC BY-SA

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