Medical research

For large bone injuries, it's Sonic hedgehog to the rescue

A USC Stem Cell study in npj Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key to this repair ...

Medical research

Resistance mechanisms to CAR-T cell therapy ID'd in ALL

For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...

Genetics

Study identifies key regulator of cell differentiation

Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body. Scientists have long sought to understand the signals that prompt stem cells to switch off ...

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