Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

Oncology & Cancer

New maps link thousands of genetic variants to disease genes

Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...

Obstetrics & gynaecology

Progesterone from an unexpected source may affect miscarriage risk

About twenty percent of confirmed pregnancies end in miscarriage, most often in the first trimester, for reasons ranging from infection to chromosomal abnormality. But some women have recurrent miscarriages, a painful process ...

Genetics

Big data provides clues for characterizing immunity in Japanese

Although genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6 in a segment called the major histocompatibility complex (MHC) region. The density ...

Obstetrics & gynaecology

Accepted manuscripts meet more criteria for research reporting

(HealthDay)—Accepted manuscripts for observational studies have better adherence to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist compared with rejected manuscripts, according ...

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