Medical research

Sugar chains on cell surfaces direct cancer cells to die

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...

Medical research

Sweetening the deal on bone repair

By replacing or replenishing injured tissue with biomimetic structures, scientists can help initiate stem cell-driven repair cascades throughout the body. Insights from an A*STAR-led study of the interactions between bone ...

Immunology

New method enables creation of better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to ...

Medical research

Insights into a rare genetic disease

Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding ...

Oncology & Cancer

Cancer cells' communication path blocked

Lund University cancer researchers have discovered the path used by exosomes to enter cancer cells, where they stimulate malignant tumour development. They have also succeeded in blocking the uptake route in experimental ...

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