Oncology & Cancer

Cancer mutations caused by bacterial toxin preventable

Reports show that cancer is the second leading cause of death globally. Scientists from Duke-NUS Medical School have found DNA mutations in some cancers that link them to a bacterial toxin called colibactin. Their findings, ...

Oncology & Cancer

Researchers find a new therapeutic target in pancreatic cancer

The development of pancreatic cancer is driven by co-existing mutations in an oncogene involved in controlling cell growth, called KRAS, and in a tumor suppressor gene, called p53. But how these mutations cooperate to promote ...

Medical research

'Terminator' protein halts cancer-causing cellular processes

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

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