Oncology & Cancer
Targeting ras with protein engineering
A review paper titled "Targeting Ras with protein engineering" has been published in Oncotarget.
Nov 27, 2023
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News tagged with surface molecules
HIV & AIDS
Inhibiting a metabolic regulator in specialized immune cells increases inflammation
Therapeutically inhibiting a metabolic regulator in monocytes unexpectedly increased inflammatory signaling, according to a study published in the journal Communications Biology.
Sep 16, 2022
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Oncology & Cancer
Researchers identify specific cells that contribute to the pathology of myasthenia gravis combined with thymus tumor
Autoimmune diseases occur when a person's antibodies mistakenly recognize their body's own cells as foreign invaders and attack them. One such disease is myasthenia gravis (MG), where the antibodies target neuromuscular-associated ...
Jul 28, 2022
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Genetics
Olfactory neurons adapt to the surrounding environment
Olfactory receptors, present on the surface of sensory neurons in the nasal cavity, recognize odorant molecules and relay this information to the brain. How do these neurons manage to detect a large variability of signals ...
May 30, 2022
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51
Oncology & Cancer
Switching off the 'survival protein' for cancer cells
Proteins control almost all vital processes in our cells. If they do not function correctly, if there is too much or too little of them, this can lead to the development of a variety of diseases including cancer. The associated ...
Mar 9, 2021
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Diseases, Conditions, Syndromes
Discovery pinpoints new therapeutic target for atopic dermatitis
Researchers from Trinity have discovered a key mechanism underlying bacterial skin colonisation in atopic dermatitis, which affects millions around the globe.
Jan 11, 2021
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Medical research
New molecule stops drug cravings in mice, with fewer side effects
Duke University researchers have developed a synthetic molecule that selectively dampen the physiological rewards of cocaine in mice. It also may represent a new class of drugs that could be more specific with fewer side ...
May 28, 2020
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202
Oncology & Cancer
Eye and the scalpel: Ocular tumors easier to diagnose noninvasively
Australia is the sunniest continent on Earth—which is why it also has the highest rates of skin cancer. But plentiful sunlight is also likely responsible for the lesser known ocular surface cancer, which occurs when abnormal ...
Apr 2, 2020
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Oncology & Cancer
Leukemia drugs hold promise for treatment-resistant lung cancer
Two recently approved leukemia drugs could be enlisted against treatment-resistant lung cancer, with a clinical trial expected to launch in Toronto and Zagreb, Croatia, later this year to evaluate one of them.
Feb 24, 2020
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122
Medical research
New opportunity for cancer drug development
After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are ...
Jan 21, 2020
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