Neuroscience

How synaptic vesicles accumulate glutamate

In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...

Neuroscience

Calcium channels regulate neuroinflammation and neuropathic pain

Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...

Genetics

Discovery gives insight into brain function, breakdowns

Scientists at Oregon Health & Science University have identified a long-sought gene-encoded protein that enables the brain to communicate a broad range of signals across gaps between neurons, known as synapses. The discovery ...

Neuroscience

One dose of alcohol is enough to modify the brain

A research team from the University of Cologne and the Universities of Mannheim and Heidelberg has found that even the single administration of alcohol permanently alters the morphology of neurons. In particular, the structure ...

Neuroscience

How does the brain learn?

Everyone knows the human brain is extremely complex—but how does it learn, exactly? Well, the answer may be a lot simpler than commonly believed.

Diseases, Conditions, Syndromes

Researchers redefine the mechanisms of Dravet syndrome

Researchers from Children's Hospital of Philadelphia (CHOP) have found that dysfunction in an important cell subtype in the brain's neuronal network contribute to chronic symptoms in the neurodevelopmental disorder Dravet ...

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