Schizophrenia is a severe mental disorder characterized by positive symptoms, negative symptoms, and cognitive deficits, with heritability estimates of approximately 80%. Synaptic dysfunction is a core component of the pathophysiology ...
Apr 10, 2024
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Northwestern Medicine investigators have developed a method to measure protein expression in an individual neuron, a discovery that will enable scientists to study how this process goes awry in disease, according to a study ...
Apr 8, 2024
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A neurotransmitter previously thought only to calm neurons may also play a role in waking them up, according to a study published in the journal PLOS Biology, a discovery which challenges the textbook view of how neurons ...
Feb 23, 2024
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Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders. Every year, new genetic mutations or protein dysregulations are identified as potential ...
Jan 4, 2024
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Retinal degeneration in the disease retinitis pigmentosa is caused by a family of hereditary mutations that slowly lead to blindness over years or decades. A mouse model of one of these forms of retinitis pigmentosa, RP59, ...
Oct 31, 2023
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A new article published in Acta Pharmaceutica Sinica B discusses how gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects.
Oct 16, 2023
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Investigators have identified new signaling mechanisms utilized by endocannabinoids to regulate a subset of neurons in response to stress, according to findings published in the Proceedings of the National Academy of Sciences.
Oct 6, 2023
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A research team from University of Lausanne (UNIL) and the Wyss Center, has discovered a new type of cell essential for brain function. Hybrid in composition and function, in between the two types of brain cells known so ...
Sep 6, 2023
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In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...
Jun 6, 2023
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A new research paper was published in Aging, titled "Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats."
Apr 19, 2023
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