Neuroscience

How synaptic vesicles accumulate glutamate

In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...

Neuroscience

Calcium channels regulate neuroinflammation and neuropathic pain

Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...

Neuroscience

One dose of alcohol is enough to modify the brain

A research team from the University of Cologne and the Universities of Mannheim and Heidelberg has found that even the single administration of alcohol permanently alters the morphology of neurons. In particular, the structure ...

Neuroscience

How does the brain learn?

Everyone knows the human brain is extremely complex—but how does it learn, exactly? Well, the answer may be a lot simpler than commonly believed.

Diseases, Conditions, Syndromes

Researchers redefine the mechanisms of Dravet syndrome

Researchers from Children's Hospital of Philadelphia (CHOP) have found that dysfunction in an important cell subtype in the brain's neuronal network contribute to chronic symptoms in the neurodevelopmental disorder Dravet ...

Medical research

Shootin1a—the missing link underlying learning and memory

In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...

Neuroscience

Synaptic transmission: Not a one-way street

Information flows in a well-defined direction in the brain: Chemical and electrical signals are passed from one neuron to the other across the synapse, from the pre-synaptic to the post-synaptic neuron. Now, Peter Jonas and ...

Neuroscience

Research shows how stress remodels the brain

Research led by Si-Qiong June Liu, MD, Ph.D., Professor of Cell Biology and Anatomy at LSU Health New Orleans School of Medicine, has shown how stress changes the structure of the brain and reveals a potential therapeutic ...

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