Medical research

Key drug target shown assembling in real-time

Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout ...

Neuroscience

How manganese produces a parkinsonian syndrome

Using X-ray fluorescence at synchrotrons DESY and ESRF, researchers in the Centre d'Etudes Nucléaires de Bordeaux Gradignan (CNRS/Université de Bordeaux) have demonstrated the consequences of a mutation responsible for ...

Oncology & Cancer

Microbeam radiation therapy

Both the efficacy and side effects of radiation therapy depend not only on the exposure dose but also on the volume of tissue exposed to that radiation. As a general rule, the smaller the volume, the greater the tolerance. ...

Medical research

Research teams unite for research on Lou Gehrig's Disease

Lisa Miller and Paul Gelfand, biophysical chemists at the U.S. Department of Energy's Brookhaven National Laboratory, recently visited the Advanced Photon Source at Argonne National Laboratory to supplement their research ...

Ophthalmology

Research poised to lead to major advances in cataract treatment

(Medical Xpress)—Research carried out by Professor Barbara Pierscionek and a team of fellow vision experts suggests that the way proteins are distributed in the lens of the eye may cause its gradient to be stepped rather ...

Medical research

Scattered X-rays improve early detection of pulmonary disease

Severe lung diseases are among the leading causes of death worldwide. To date they have been difficult to diagnose at an early stage. Within an international collaboration scientists from Munich now developed an X-ray technology ...

Medical research

An earlier diagnosis to avoid kidney transplants

An analytical technique using high brilliance infrared light produced by the SOLEIL synchrotron has been developed by teams from the CNRS, Paris Sud University, Tenon Hospital in Paris, and the Stoke-on-Trent Cancer Centre ...

Medical research

Model of enzyme's structure could spur new therapies

In many pharmaceutical company and university laboratories, scientists are looking closely at kinase complexes because the enzymes play key roles in essential cell functions. By taking unusual steps to examine a kinase complex, ...

Medical research

Researchers uncover details of joint injuries in children

Scientists working in part at the National Synchrotron Light Source (NSLS) have learned new information about how the knee joints of children are damaged as the result of a compression injury, which could happen during sports ...

Medical research

Elucidation of the 3D structure of Chikungunya virus

French researchers at the Pasteur Institute and the CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional structures of the glycoproteins that envelop the chikungunya virus. This discovery ...

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