Oncology & Cancer

A helping hand for cancer immunotherapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...

HIV & AIDS

Existing drugs may limit damage caused by HIV

Yale researchers have identified four drugs that may help minimize the long-term health effects of HIV infection, they report June 23 in the Journal of Clinical Investigation.

Immunology

ANCA-associated vasculitis: The ADVOCATE study

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation. There are several diseases associated ...

Psychology & Psychiatry

Impressive result for mental health therapy

The researchers evaluated the NewAccess program, which is an Australian adaptation of the United Kingdom's IAPT (Improving Access to Psychological Therapies) approach of delivering low intensity therapies for symptoms of ...

Immunology

New drug combinations help overcome resistance to immunotherapy

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations ...

Medical research

Patients improve after heart cell therapy

Four of six critically ill COVID-19 (coronavirus) patients significantly improved after receiving an experimental therapeutic designed to reduce inflammation, a major cause of death from this disease, according to a case ...

Alzheimer's disease & dementia

Psoriasis tied to higher Alzheimer disease risk

(HealthDay)—The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean study published online April 15 in Scientific Reports.

Medical research

Novel technology aims to improve treatment of neurological diseases

A recently developed system for switching on the activity of genes could improve treatments for a broad range of neurological diseases. Esteban Engel, a researcher in viral neuroengineering in the Princeton Neuroscience Institute, ...

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