Medical research

Using 'organs-on-a-chip' to model complicated diseases

MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.

Oncology & Cancer

Cancer: The immune system attacks tumors remotely

How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating T lymphocytes, both locally ...

Medical research

S1P and its receptor: New approaches to cancer?

In 1998, when Timothy Hla, Ph.D., and his colleagues identified and cloned the receptor for sphingosine-1-phosphate (S1P), it generated a lot of excitement. S1P, a lipid originally discovered in the 1960s, was known to play ...

Immunology

Specialized helper cells contribute to immunological memory

Helper T cells play an important role in the immune response against pathogens. The role of a particular subset of these immune cells was previously unclear. It's now been shown that T follicular helper cells live much longer ...

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