Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant ...
May 9, 2022
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In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, ...
Apr 14, 2022
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Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...
Mar 16, 2022
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People who gained immunity—either through vaccination or exposure—against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's Omicron variant. ...
Mar 11, 2022
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For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram ...
Feb 28, 2022
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Infection with SARS-CoV-2 leaves some people almost unaffected, while others develop life-threatening COVID-19 symptoms. So far, we do not understand exactly why symptoms and disease severity, especially in infections with ...
Feb 3, 2022
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SARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the person's own body. This process, known as "autoimmunity," can damage a number of different organs.
Sep 23, 2021
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A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold" tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can ...
Sep 10, 2021
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Every four minutes, someone in the United States is diagnosed with a type of blood cancer, such as lymphoma or leukemia. According to the American Cancer Society's estimates, approximately 60,530 cases of leukemia and 90,000 ...
Sep 9, 2021
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Researchers at Uppsala University have discovered lymph node-like structures close to the tumour in brain cancer patients, where immune cells can be activated to attack the tumour. They also found that immunotherapy enhanced ...
Jul 5, 2021
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