Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose ...
Dec 11, 2022
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Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury ...
Jan 6, 2021
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Dendritic cells, discovered in 1973 by Ralph Steinman (2011 Nobel prize in Physiology or Medicine) and known for their role as sentinels of the immune system, have an essential function in the development of high endothelial ...
Nov 17, 2011
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Research led by the University of Sydney, Australia, has uncovered an important driver of critical SARS-CoV-2 infections. In their paper, "A unique cytotoxic CD4+ T cell-signature defines critical COVID-19," published in ...
Julien Diana and Yannick Simoni of the "Immune Mechanisms in Type 1 Diabetes," Inserm/Université Paris Descartes, directed by Agnès Lehuen, have just published the results of their work on type 1 diabetes in the Nature ...
Dec 19, 2012
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RUDN biochemists suggested a new mechanism by which the human body prevents the development of autoimmune diseases, allergies and implant rejection. They report that regulatory T-cells are able to suppress the reproduction ...
Sep 10, 2018
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Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...
Mar 16, 2022
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In the immune system's fight against cancer and infections, the T cells often lose their power. The team of Würzburg immunologist Martin Vaeth has found a possible explanation for this phenomenon.
Nov 2, 2023
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(Medical Xpress) -- Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more ...
Sep 21, 2011
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HIV patients treated with genetically modified T cells remain healthy up to 11 years after initial therapy, researchers from the Perelman School of Medicine at the University of Pennsylvania report in the new issue of Science ...
May 2, 2012
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