How does the immune system act to limit tumor development? Using in vivo imaging tools, scientists from the Institut Pasteur and Inserm described the spatiotemporal activity of tumor-infiltrating T lymphocytes, both locally ...
Mar 12, 2020
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211
It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome—about six feet of DNA—is compressed into the micrometer ...
Feb 11, 2020
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51
Scientists at the University of Dundee have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumours.
Oct 7, 2019
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In a discovery that might be likened to finding medicine's version of the Loch Ness monster, a research team from Johns Hopkins Medicine, IBM Research and four collaborating institutions is the first to document the existence ...
May 30, 2019
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Immunologist Frances Lund, Ph.D., and colleagues have detailed the role of a key controlling factor in the transformation of B cells into antibody-secreting cells, the cells that produce antibodies to fight invading pathogens ...
May 7, 2019
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Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand ...
Feb 26, 2019
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The idea of a cancer vaccine is something researchers have been working on for over 50 years, but until recently they were never able to prove exactly how such a vaccine would work.
Dec 6, 2018
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A single leukemia cell, unknowingly engineered with the leukemia-targeting chimeric antigen receptor (CAR) lentivirus and infused back into a patient, was able to reproduce and cause a deadly recurrence of B-cell acute lymphoblastic ...
Oct 1, 2018
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The doctors who have spent years studying the case call it "a series of fortunate events." What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome ...
May 30, 2018
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Using technologies and computational modeling that trace the destiny of single cells, researchers at the University of California, San Diego School of Medicine describe for the first time the earliest stages of fate determination ...
Mar 2, 2014
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