Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine.
May 22, 2011
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Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School ...
Jul 25, 2014
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An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward ...
Sep 8, 2016
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Patterns of radiation usage in breast conserving therapy for women 70 years and older with stage I breast cancer are changing: more women are opting for radioactive implants and those with estrogen positive tumors are opting ...
Jun 2, 2011
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The benefits of using tamoxifen to prevent recurrence of breast cancer after surgery continue to accrue long after women stop taking the drug, a study led by Oxford University has found.
Jul 29, 2011
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Despite the overall success of hormone therapy, breast cancer tumors in patients with metastatic disease often fail to respond. One new mechanism that can explain resistance to hormone therapy in breast cancer involves two ...
Oct 4, 2016
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An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen ...
Feb 1, 2018
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(HealthDay)—Researchers have identified genes that may help predict whether a patient with estrogen receptor (ER)-positive breast cancer is likely to benefit from tamoxifen therapy, according to a study published in the ...
Jul 22, 2014
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The largest study to investigate the tolerability of the breast cancer drug tamoxifen in male breast cancer patients has shown that men stop taking their prescribed therapy early because of problems with side effects caused ...
Nov 16, 2011
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Stopping the spread of Shiga toxins released by E. coli bacteria, which are potentially fatal if they reach the kidneys, has been a focus of researchers for years. No treatments for STEC currently exist, and antibiotic therapy ...
Jul 1, 2019
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