Oncology & Cancer
Breast cancer drug could create chink in the armour of pancreatic cancer
The well-known drug tamoxifen could exploit a weakness in the physical 'scaffolds' around tumours, according to research led by Imperial.
Dec 11, 2018
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News tagged with tamoxifen
Oncology & Cancer
Low-dose tamoxifen safe and effective at reducing recurrence of DCIS, LCIS, and ADH
Treatment with a low dose of tamoxifen (5 mg per day) halved the risk of disease recurrence and new disease for women who had been treated with surgery following a diagnosis of breast intraepithelial neoplasia compared with ...
Dec 6, 2018
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Oncology & Cancer
Women reveal the reasons they reject a preventive drug for breast cancer
Only around a fifth of women at higher risk of developing breast cancer think they need to take a drug proven to help prevent the disease, according to new research funded by Cancer Research UK and published today (Monday) ...
Dec 3, 2018
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Oncology & Cancer
Osteoporosis risk rises sharply even for younger breast cancer survivors
Women diagnosed with breast cancer who are 50 or younger face a much higher risk of the bone-loss condition osteoporosis compared to women of the same age who do not have cancer. The findings, which complement prior research ...
Nov 29, 2018
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Medical research
A molecule for fighting muscular paralysis
Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva (UNIGE), ...
Nov 19, 2018
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Oncology & Cancer
One in six premenopausal early breast cancer patients do not adhere to hormonal therapy
Nearly one in six premenopausal women being treated for early stage breast cancer do not adhere adequately to tamoxifen therapy after one year of treatment, potentially putting themselves at increased risk of recurrence and ...
Oct 19, 2018
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Surgery
Extended tamoxifen therapy may increase risk of endometrial cancer
There is clear evidence that extended adjuvant tamoxifen therapy for 10 years reduces local recurrence and improves breast cancer-free survival in women with oestrogen receptor-positive breast cancer. An analysis of large ...
Jul 5, 2018
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Oncology & Cancer
ASCO: ovarian suppression + tamoxifen ups breast CA survival
(HealthDay)—The addition of ovarian suppression to tamoxifen is associated with increased survival versus tamoxifen alone among premenopausal women with breast cancer, according to a study published online June 4 in the ...
Jun 5, 2018
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Oncology & Cancer
AI plus ovarian suppression yields benefit in high-risk younger breast cancer patients
Premenopausal women with hormone receptor-positive, HER2-negative breast cancer and a high risk of recurrence who are treated with an aromatase inhibitor plus ovarian function suppression may gain 10 to 15 percent improvement ...
Jun 4, 2018
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Medical research
Tamoxifen and raloxifene slow down the progression of muscular dystrophy
Steroids are currently the only available treatment to reduce the repetitive cycles of inflammation and disease progression associated with functional deterioration in patients with muscular dystrophy (MD). A study reported ...
Mar 20, 2018
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