Extracellular vesicles (EV) represent a promising vector system for biomolecules and drug delivery due to their natural origin and participation in intercellular communication. As the quantity of EVs is limited, the researchers ...
Apr 24, 2018
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Scientists have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.
Apr 20, 2018
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Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers have discovered that accumulation of a type of lipid (fat), known as ceramides, plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition ...
Mar 6, 2018
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A possible first-line treatment for a rare bone loss disease has been identified by a research team led by Tohoku University in Japan. The research findings, published in the journal Molecular Cell, could also provide insight ...
Feb 7, 2018
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A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to ...
Dec 14, 2017
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A protein called disrupted-in-schizophrenia 1, encoded by the DISC1 gene, has been established as a genetic risk factor for a wide array of psychiatric disorders, including schizophrenia, bipolar disorder, major depression, ...
Dec 14, 2017
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Researchers at the Francis Crick Institute have discovered a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies.
Oct 17, 2017
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Chagas disease is a potentially life-threatening illness caused by the parasite Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking insects commonly referred to as "kissing bugs" or "vampire bugs." ...
Sep 26, 2017
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There may no silver bullet for treating liver cancer or fatty liver disease, but knowing the right targets will help scientists develop the most effective treatments. Researchers in Sweden have just identified a number of ...
Aug 22, 2017
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COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, ...
May 10, 2017
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