Genetics

Unravelling the genetic mystery behind mitochondrial disease

Researchers from the Monash Biomedicine Discovery Institute in Melbourne have identified two new genes linked to a major cause of mitochondrial disease. Their research opens the way for better genetic diagnosis of the disease ...

Medical research

Researchers identify important signaling molecule

An international team of scientists have provided insights into the working of a "signaling molecule", which will provide new strategies for medicines in areas such as pain medication.

Medications

Supercomputers link proteins to drug side effects

New medications created by pharmaceutical companies have helped millions of Americans alleviate pain and suffering from their medical conditions. However, the drug creation process often misses many side effects that kill ...

Medical research

Mechanism of action of thalidomide elucidated

(Medical Xpress)—Scientists led by Nicolas Thomä at the Friedrich Miescher Institute for Biomedical Research have clarified the workings of thalidomide at the molecular level. Their analysis of various structures, published ...

Medical research

New computational method exploits the polypharmacology of drugs

(Medical Xpress)—If life were simple, a disease could be treated with one drug that hits one molecular target, like striking a piano key. Instead, researchers wrestle with the fact that most drugs hit multiple targets in ...

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