Two pathologies drive the progression of Alzheimer's disease. Early on, amyloid beta plaques lead the way, but around the time cognitive symptoms arise, tau tangles take over as the driving force and cognition steadily declines. ...
Jul 13, 2023
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Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates—a telltale sign of Alzheimer's brain pathology—never ...
May 29, 2023
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Researchers at the University of Arizona College of Medicine–Tucson, along with collaborators at Harvard University, harnessed the power of artificial intelligence to identify causes of Alzheimer's disease and potential ...
May 16, 2023
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Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative ...
Feb 14, 2023
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Sometimes in science, "Eureka!" moments happen with surprisingly little effort. Sometimes they take years or decades to emerge. Such was the case with Brian Kraemer's research team and their recent study of the protein tau ...
Feb 6, 2023
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A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was ...
Dec 27, 2022
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Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there's no easy way to distinguish among people living with any of the primary tauopathies—a group of ...
Nov 24, 2022
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Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first ...
Nov 16, 2022
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Neurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 years and older) compared to cognitively average peers, individuals with early-stage Alzheimer's ...
Sep 30, 2022
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Researchers at the School of Dentistry, University of Central Lancashire (UCLan) were the first to report the link between gum disease and Alzheimer's disease.
Sep 22, 2022
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