Diseases, Conditions, Syndromes

Successful TB vaccine moves forward after phase 2 trial

Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine. The three-year trial was conducted ...

Diseases, Conditions, Syndromes

How blocking iron drives the lung immune system to control infection

Although COVID-19 commands the headlines today, tuberculosis (TB) remains the biggest infection killer in the world and multiple drug resistant TB, which does not respond to regular antibiotics, continues to be a major threat ...

Diseases, Conditions, Syndromes

Immune responses to tuberculosis mapped across three species

Tuberculosis (TB) is one of the world's most vexing public health problems. About 1.5 million people died from this bacterial lung infection in 2018, and the World Health Organization (WHO) estimates that one-quarter of the ...

Diseases, Conditions, Syndromes

New animal model shows effective treatment for latent tuberculosis

A major goal of tuberculosis (TB) research is to find a way to treat people with the latent (or inactive) form of the disease to keep them from developing symptomatic TB. A breakthrough study using a new animal model developed ...

Diseases, Conditions, Syndromes

Tuberculous infection is not life-long in most people

A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis (TB). Based on a review of clinical studies, researchers from the ...

Diseases, Conditions, Syndromes

12.6 million in U.S. could benefit from therapy to prevent active TB

(HealthDay)—An estimated 12.6 million persons in the United States could benefit from treatment to prevent active tuberculosis (TB), according to a report published in the October issue of Emerging Infectious Diseases, ...

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