Oncology & Cancer

Proteogenomics identifies novel acute myeloid leukemia subtypes

In order to better treat patients diagnosed with acute myeloid leukemia (AML), the pathological processes and also existing subtypes of the disease must be better understood. With the help of proteome and genome analysis, ...

Medical research

Study offers promising approach to reducing plaque in arteries

In a new Yale-led study, investigators have revealed previously unknown factors that contribute to the hardening of arteries and plaque growth, which cause heart disease. Their insight is the basis for a promising therapeutic ...

Oncology & Cancer

Stopping anti-CCL2 breast cancer treatment aggravates the disease

Mohamed Bentires-Alj and his team at the Friedrich Miescher Institute for Biomedical Research (FMI) together with scientists from the Novartis Institutes for BioMedical Research (NIBR) show in a study published today in Nature ...

Medical research

Decoy FGFR3 protein appears to prevent dwarfism in mice

(Medical Xpress)—A team made up of researchers from several institutions in France has found that a decoy protein injected into mice, appears to prevent the development of dwarfism. In their paper published in the journal ...

Parkinson's & Movement disorders

Not guility: Parkinson and protein phosphorylation

Clues left at the scene of the crime don't always point to the guilty party, as EPFL researchers investigating Parkinson's disease have discovered. It is generally accepted that the disease is aggravated when a specific protein ...

Medical research

New signal stabilizes atherosclerotic plaques

Atherosclerosis is an inflammatory disease with accumulation of cholesterol in the vessel walls. The atherosclerotic plaque is built up throughout life and when it ruptures it leads to heart attack or stroke. T cells are ...

Cardiology

Cells make costume changes for cardiac regeneration

(Medical Xpress)—If the heart following a heart attack is not sufficiently supplied with blood, heart tissue dies. In adult humans, the ability to heal itself is hardly developed. Scientists from the Max Planck Institute ...

Neuroscience

Researchers target an aspect of Down syndrome

University of Michigan researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic ...

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