Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19. A key enzyme in this process is thrombin. To date, no method ...
Aug 10, 2023
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Blood-feeding animals rely on specific molecules in their saliva to overcome defense mechanisms of their mammalian hosts for successful survival. For example, tick saliva contains molecules that can stop blood from clotting, ...
Dec 6, 2021
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Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients. The exact cause remains unclear, and there ...
May 6, 2020
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Salk researchers have found, for the first time, that a blood-clotting protein can, unexpectedly, degrade nerves—and how nerve-supporting glial cells, including Schwann cells, provide protection. The findings, published ...
Mar 14, 2019
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The protein thrombin is vital for ensuring blood coagulates in a wound, but new research suggests small fragments of it, called thrombin-derived C-terminal peptides (TCPs), could also decrease the risk of sepsis in response ...
Dec 20, 2018
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Researchers have designed tiny, light-controlled gold particles that can release DNA controls to switch blood clotting off and on. The results are reported July 24 in the open access journal PLoS ONE by Kimberly Hamad-Schifferli ...
Jul 24, 2013
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Researchers, including Professor Alastair Poole and Dr Matthew Harper from the University of Bristol's School of Physiology and Pharmacology, have uncovered a key process in understanding how blood clots form that could help ...
Jun 26, 2013
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(Medical Xpress)—It takes more than platelets, thrombin and fibrin to build a deep vein thrombosis (DVT). Increasingly, researchers are recognizing that neutrophils—cells better known for their role in immune defense—play ...
May 31, 2013
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New insights into what causes uncontrollable bleeding in hemophilia patients are provided in a study published by Cell Press on November 20th in the Biophysical Journal. By revealing that blood clots spread in traveling waves ...
Nov 20, 2012
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