Cardiology

No improvements with losmapimod after heart attack

Patients taking losmapimod, an anti-inflammatory drug currently being developed, for 12 weeks following a heart attack did not show improvements in the trial's primary endpoint, the rate of cardiovascular death, subsequent ...

Alzheimer's disease & dementia

Mesh-like scaffold is disordered in Alzheimer's-affected cells

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio ...

Cardiology

Protein helps protect tissues from damage after a heart attack

University of Cincinnati (UC) researchers have observed levels of HAX-1, an anti-cell death protein, drop significantly in mice after a heart attack and during heart failure resulting in cardiac cells dying at a higher than ...

HIV & AIDS

Blood T cells are resistant to HIV's primary death pathway

Scientists from the Gladstone Institutes have discovered that blood-derived T cells are resistant to the chief cause of cell death in HIV infection. Instead, it is T cells in the lymphoid tissues that are most susceptible ...

Oncology & Cancer

Starving cancer cells of sugar could be the key to future treatment

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. ...

HIV & AIDS

HIV particles do not cause AIDS, our own immune cells do

Researchers from the Gladstone Institutes have revealed that HIV does not cause AIDS by the virus's direct effect on the host's immune cells, but rather through the cells' lethal influence on one another.

Medical research

Study IDs 'master' protein in pulmonary fibrosis

This spring has brought rare but tangible moments of progress against the devastating lung disease idiopathic pulmonary fibrosis (IPF), which afflicts millions of people worldwide. Two drugs recently showed promise in clinical ...

Cardiology

Developing drugs to reduce brain impairment after stroke

Stroke claims five million lives worldwide each year and is the second biggest killer after ischaemic heart disease. Of those who survive, a significant number (around five million) live with neurological deficits that profoundly ...

Oncology & Cancer

Scientists discover new protein involved in lung cancer

Scientists from The University of Manchester – part of the Manchester Cancer Research Centre (MCRC) - have discovered a new protein that is involved in cancer and inflammation in lung tissue.

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