Cardiology
New link found between alcohol, genes and heart failure
The researchers investigated faulty versions of a gene called titin which are carried by one in 100 people or 600,000 people in the UK.
May 25, 2018
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News tagged with titin
Cardiology
New study illuminates the biology of a common heart disorder
Researchers at Penn Medicine have made a major advance in understanding the biology of a common, puzzling, and often fatal heart disorder, dilated cardiomyopathy (DCM), which features the enlargement of the heart and a progressive ...
Nov 3, 2021
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154
Medical research
Tracking titin in real time
Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into ...
Dec 13, 2019
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50
Cardiology
Restoring heart elasticity in a heart failure model
Patients with heart failure often have shortness of breath and become fatigued quickly. They frequently suffer from water retention, heart palpitations, and dizziness. The condition can be triggered by a combination of elevated ...
Dec 1, 2021
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41
Medical research
Researchers discover reversible mechanism that increases muscle elasticity
How does yoga improve your flexibility? In the Mar 13 cover story of Cell, Columbia University biological sciences professor Julio Fernandez and team report the discovery of a new form of mechanical memory that adjusts the ...
Mar 13, 2014
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Cardiology
Diabetes drug could be used to treat common heart failure syndrome, study suggests
Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction (HFpEF), a condition that ...
Dec 19, 2018
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Genetics
Moving a cardiac regulatory protein to the right place
The largest known protein, titin, named for the Titan giants of Greek mythology, is a molecular spring found in cardiac muscle. It provides structural support and maintains tension during muscle stretching. Mutations in the ...
Jun 28, 2018
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Medical research
Physiologist publishes findings on the role of the protein titin in muscle contraction
In the field of muscle physiology, scientists study muscle movement at the molecular level—chiefly, proteins such as myosin, actin and titin—to understand how muscles contract.
Oct 8, 2018
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9
Genetics
New study reveals titin gene mutations affect heart function in healthy individuals
A new multinational study by researchers from Singapore, the UK and Germany has discovered that gene mutations in a protein called titin affect the heart function in healthy individuals. It was previously thought that the ...
Nov 21, 2016
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Cardiology
Protein dynamics in the beating heart
The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover.
Dec 18, 2019
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