Immunology

Connective tissue protein fights bacterial infection

A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition called sepsis, a new study ...

Immunology

Antioxidant protein inside the cell worsens inflammation outside

A protein that provides essential protection against free radicals inside the cell provokes damaging inflammation when released outside, activating immune cells and worsening damage following a stroke, according to a new ...

Immunology

Exploring the frontiers of immunity and healing

During a 1989 lecture at the Cold Spring Harbor Symposium on Quantitative Biology, Yale School of Medicine professor Charles Janeway, MD, hypothesized the existence of an innate immune system and special receptors on immune ...

Immunology

How immune cells switch to attack mode

Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down pathogens instead. Upon coming into contact with bacteria ...