Neuroscience

Nanotubes enable travel of Huntington's protein

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

Diseases, Conditions, Syndromes

Toward a blood test for early-stage liver disease

One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...

Diseases, Conditions, Syndromes

When sequencing fails to pinpoint a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in ...

Medical research

Blocking toxic-protein production in ALS

Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...

Oncology & Cancer

Scientists design protein that prods cancer-fighting T-cells

Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2).  IL-2 is a potent anticancer drug and ...

Neuroscience

A new hope in treating neurodegenerative disease

A research team led by Professor Sung Bae Lee of Brain and Cognitive Sciences and Professor Daehee Hwang of New Biology (vice-head of the Plant Age and Life Research Group, IBS) has identified the early neuropathological ...

Neuroscience

Neurons with good housekeeping are protected from Alzheimer's

Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University ...

Surgery

How a common drug causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently ...

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