Alzheimer's disease & dementia

Uncovering one of the driving forces of Alzheimer's disease

Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

Medical research

Targeting gene therapy directly into the lungs

Tufts researchers are building a reputation for precision targeting in drug delivery. Their tools: tiny lipid-based nanoparticles (LNPs) fine-tuned to latch on to specific tissues, organs, even cell types within the body. ...

Alzheimer's disease & dementia

A new model of Alzheimer's progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease ...

Neuroscience

New Alzheimer's treatment idea targets tau

A new idea for treating Alzheimer's disease could eradicate the toxic proteins most closely linked to cognitive decline in the places where they do the most damage, a study from researchers at Columbia University Vagelos ...

Genetics

Scientists develop breath test for methylmalonic acidemia

Researchers at the National Institutes of Health have developed a breath test that measures how well patients with methylmalonic acidemia (MMA) respond to receiving liver or combined liver and kidney transplantation. Researchers ...

Medical research

Cancer drug lessens the toxicity of a protein from COVID-19 virus

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2—the virus that causes COVID-19—and then used an FDA-approved cancer drug to blunt the viral protein's ...

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