Neuroscience

New Alzheimer's treatment idea targets tau

A new idea for treating Alzheimer's disease could eradicate the toxic proteins most closely linked to cognitive decline in the places where they do the most damage, a study from researchers at Columbia University Vagelos ...

Medical research

Cancer drug lessens the toxicity of a protein from COVID-19 virus

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2—the virus that causes COVID-19—and then used an FDA-approved cancer drug to blunt the viral protein's ...

Oncology & Cancer

Aggregated waste in brain tumors predict disease severity

Proteins are crucial to all cellular processes. So for a cell to stay viable, it has to keep its proteins in shape. In technical terms, it's called protein folding, and it refers to the process by which proteins assume their ...

Diseases, Conditions, Syndromes

Research finds new approach to treating certain neurological diseases

A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive ...

Neuroscience

Protein shapes matter in Alzheimer's research

Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.

Neuroscience

Nanotubes enable travel of Huntington's protein

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

Oncology & Cancer

Scientists design protein that prods cancer-fighting T-cells

Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2).  IL-2 is a potent anticancer drug and ...

Neuroscience

Neurons with good housekeeping are protected from Alzheimer's

Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University ...

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