Medical research

Sugar chains on cell surfaces direct cancer cells to die

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...

Oncology & Cancer

The mechanisms behind cancer cell resistance to TRAIL treatment

Researchers at Koç University discovered why a promising class of cancer treatments fail, and their findings point to how such treatments might be made to work. The research revealed the mechanisms behind the development ...

Medical research

Discovery points to new ways to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy. Michael King, chair of the Department of Biomedical Engineering, and Joshua D. Greenlee, graduate ...

Immunology

A new pathway to 'reprogram' killer cells

The so-called natural killer (NK) cells are cells of the innate immune system that recognize and eliminate infected cells or cancer cells. During a virus infection, NK cells also keep the body's own immune cells such as the ...

Oncology & Cancer

Gene-targeted cancer drugs, slow release overcome resistance

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve ...

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