Neuroscience
A new strategy for repairing DNA damage in neurons
"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.
Feb 15, 2023
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News tagged with transcription
Diabetes
'Tiny but mighty' gene fragments are crucial for maintaining blood glucose levels, shows study
When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest. The resulting product is a fully-mature RNA molecule, which can be used as a template ...
Feb 9, 2023
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Genetics
The best genetic predictors of heart arrhythmia and hidden comorbidity
In the largest genetic study of heart arrhythmia to date, researchers led by Kazuo Miyazawa and Kaoru Ito at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the discovery of several genes and individual ...
Jan 19, 2023
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Oncology & Cancer
Scientists detail major mechanism lung cancers use to evade immune attack
A protein commonly found at high levels in lung cancer cells controls a major immunosuppressive pathway that allows lung tumors to evade immune attack, according to a study led by researchers at Weill Cornell Medicine. The ...
Jan 10, 2023
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Medical research
The molecules behind metastasis
Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage to form new tumors, and so remain dormant. The deadliest cancer cells are ...
Jan 5, 2023
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Oncology & Cancer
Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers
A team of researchers from the University of Toronto, The Hospital for Sick Children, Toronto, the Ontario Institute for Cancer Research, Georgetown University and the Memorial Sloan Kettering Cancer Center, used a computational ...
Gerontology & Geriatrics
Research illuminates approaches for long-term hearing loss treatment
About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves ...
Dec 8, 2022
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Medical research
Early life experiences can have long-lasting impact on genes
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
Dec 1, 2022
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Medical research
Ganglion cells created in mice in bid to fix diseased eyes
While fish, reptiles and even some birds can regenerate damaged brain, eye and spinal cord cells, mammals cannot. For the first time, non-neuronal cells have been induced to mimic specific ganglion cells in the eyes of mice.
Nov 30, 2022
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Oncology & Cancer
Discovery suggests new way to target mantle cell lymphoma
A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma ...
Nov 22, 2022
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